Iogate “Total” promotes dental and oral health in a totally new way. The use of Iogate Total toothpaste has the potential to significantly improve not just oral health (and dental health as part of it), but health in general.
Recent clinical evidence supports the idea that orally applied iodine lowers “bad” (LDL) cholesterol in adults.
This is because the mouth is the principal bodily entry-point for infectious disease organisms. Good health maintenance at the “front door” of the body is essential to general health. Despite this fact, is a growing incidence of dental disease throughout the world  – probably related to the ever-increasing adoption of a Western diet, high in “fast” carbohydrates and sugar, and low in fat, whole grain and plant sources.
A new approach that deals with this epidemic is long overdue. The problem is national and global.
THE NEW IOGATE APPROACH: Our new IOGATE approach has two essential elements.
First, it is based on clinical studies which demonstrate the power of iodine to prevent cavities and gingivitis. 
Second, since recent clinical studies have demonstrated that fluoride, ubiquitous in toothpaste and most municipal drinking waters, appears to cause an increase in thyroid disease, we do NOT use fluoride in our toothpaste.  Rather, we use traditional, long-proven ingredients of demonstrated safety over more than 100 years: iodine, peppermint and baking soda (sodium bicarbonate).
FLUORIDE IS TOXIC. Why consume it? Whether in water or toothpaste, it’s not a good thing to ingest, even in small quantities. (Please note that your toothpaste tube indicates that ingestion of the toothpaste – with its fluoride – can be deadly to small children.) Almost all municipal water in the U.S. is fluoridated. Fluoride, in any significant quantities, is a highly toxic poison. Not so iodine. Iodine is an essential micronutrient. Since the thyroid is a key organ in the management of cell and body metabolism, thyroid disease is a serious problem that can affect anyone – and in particular, pregnant women and their babies.
TRICLOSAN IS TOXIC: Why consume it? It is present in most toothpastes.
Iodine is an exceptionally effective promoter of oral hygiene, prevents tooth decay, and helps prevent gingivitis. IOGATE also contains sodium bicarbonate and calcium carbonate, which are natural substances useful both for disease prevention and mild abrasiveness to clean tooth surfaces. Finally, we add peppermint, which itself has antimicrobial activity and inhibits cavity formation. 
What ISN’T in IOGATE. Iogate contains ZERO:
* Triclosan is an active ingredient in many toothpastes, and can combine with chlorine in tap water to form chloroform, which the U.S. Environmental Protection Agency classifies as a probable human carcinogen. It may modify hormone regulation, and also produces antimicrobial resistance.
1. ^ The global increase in dental caries. A pending public health crisis; Robert A. Bagramian, DDS, MPH, Ph. D., et al. “A current review of the available epidemiological data from many countries clearly indicates that there is a marked increase in the prevalence of dental caries. If remedies are not initiated, there could be a serious negative impact upon the future oral health (and systemic health) of the global community, as well as a strain on the dental profession and a major increase in the cost of dental services….during the past decade, scientific report after report signal an alarming increase in the global prevalence of dental caries in children and adults, primary and permanent teeth, as well as coronal and root surfaces.” Am J Dent 2009;22:3-8.
2. ^ Effect of Povidone-iodine on Streptococcus Mutans in Children With Extensive Dental Caries; Povidone-Iodine Substantially Inhibits Cavities in Children with Extensive Caries. Amin, Maryam S. et al. “Results: Experimental and control children had similar dietary habits, caries experience, and S. mutans levels at baseline. At 1 year, 5 of 8 children in the control group had new caries compared to 2 of 11 children in the experimental group (P=. 06). Povidone-iodine was well-accepted by participating families. Conclusions: Extensive one-time restorative dental treatment resulted in a significant suppression S. mutans levels at 6 months. Further exploration of the role of povidone-iodine in caries management is indicated.” Pediatric Dentistry, Volume 26, Number 1, January/February 2004, pp. 5-10(6); American Academy of Pediatric Dentistry
3. ^ Are fluoride levels in drinking water associated with hypothyroidism prevalence in England? Epidemiological Community Health 2015;69:619-624 doi:10.1136/jech-2014-204971; S. Peckham; D Lowery; S. Spencer; Centre for Health Services Studies, University of Kent, Canterbury, Kent, UK; 24 Feb 2015. “This observational study examines the association between levels of fluoride in water supplies with practice level hypothyroidism prevalence. We found that higher levels of fluoride in drinking water provide a useful contribution for predicting prevalence of hypothyroidism. We found that practices located in the West Midlands (a wholly fluoridated area) are nearly twice as likely to report high hypothyroidism prevalence in comparison to Greater Manchester (non-fluoridated area).
In many areas of the world, hypothyroidism is a major health concern and in addition to other factors—such as iodine deficiency—fluoride exposure should be considered as a contributing factor. The findings of the study raise particular concerns about the validity of community fluoridation as a safe public health measure.”
4. ^ Antimicrobial efficacy of five essential oils against oral pathogens: An in vitro study. European Journal of Dentistry, Vol 7 / Supplement 1 / Sept 2013. Department of Pedodontics and Preventive Dentistry, Sharad Pawar Dental College, India. “Peppermint, tea tree and thyme oil can act as an effective intracanal antiseptic solution against oral pathogens.”
5. ^ Journal of Applied Toxicology. 2011 May;31(4):285-311. Triclosan: Environmental Exposure, Toxicity and Mechanisms of Action. Dann AB; Hontela A. “Triclosan [TCS] is a broad spectrum antibacterial agent used in personal care, veterinary, industrial and household products. The continuous exposure of aquatic organisms to TCS, coupled with its bioaccumulation potential, have led to detectable levels of the antimicrobial in a number of aquatic species. TCS has been also detected in breast milk, urine and plasma, with levels of TCS in the blood correlating with consumer use patterns of the antimicrobial. Concern has been raised over TCS’s potential for endocrine disruption, as the antimicrobial has been shown to disrupt thyroid hormone homeostasis and possibly the reproductive axis. The potential for endocrine disruption and antibiotic cross-resistance highlights the importance of the judicious use of TCS.”